Materal Serum Interleukin-6 and Interleukin-8 Concentrations in Patients with Premature Rupture of Membranes and Chorioamnionitis
- VernacularTitle:血清IL-6和IL-8对胎膜早破并发绒毛膜羊膜炎的监测
- Author:
Xiaoli ZHAO
;
Xiaoxing MA
;
Xiaoming SUN
- Publication Type:Journal Article
- Keywords:
Fetal membranes;
premature rupture;
Chorioamnionitis;
Interleukin-6;
Interleukin-8
- From:
Chinese Journal of Perinatal Medicine
1998;0(03):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To determine whether the maternal serum interleukin-6(IL-6)and in- terleukin-8(IL-8)concentrations can be used in the antenatal diagnosis of intrauterine infection in premature rupture of membranes(PROM).Methods The level of maternal serum IL-6 and IL-8 were determined by a sensitive enzyme-linked immunosorbent assays in 50 normal late pregnant women,25 patients with PROM but without evidence of IAI and 49 patients with PROM and IAI. Results The maternal serum IL-6 and IL-8 concentrations in patients with PROM and IAI were 301.19?142.34/L and 312.32?149.56 ng/L,which were higher than that in patients with PROM but without IAI(133.22?55.26 ng/L and 125.35?61.30 ng/L)and the normal late pregnant wom- en were(126.59?57.12 ng/L and 112.69?56.02 ng/L),P
