The influence of propofol on cerebral blood flow
- VernacularTitle:异丙酚及其血药浓度对脑血流的影响
- Author:
Wen CHEN
;
Enzhen WANG
;
Jianxiu LIU
;
- Publication Type:Journal Article
- Keywords:
Propofol Pharmacokinetics Brain Blood flow velocity
- From:
Chinese Journal of Anesthesiology
1994;0(06):-
- CountryChina
- Language:Chinese
-
Abstract:
To observe correlation between the cerebral blood flow (CBF)and plasma concentration of propofol. Method: Twenty two patients, ASA grade I, were given propofol 2mg/kg. Before and after the administra tion, the velocity of MCA(middle cerebral artery), PI(pulsaltility index) and RI(resistance index) were tested simultaneously, and the plasma concentration of propofol were measured with high performance liquid chromatography. Resuit: The mean velocity of MCA(Vmca)decreased significantly and RI increased after propofol administration(P
