Influence of open heart surgery under cardiopulmonary bypass on pancreatic beta cell function
- VernacularTitle:体外循环心内手术对胰腺?细胞功能的影响
- Author:
Feilong HEI
;
Xiusheng FANG
;
- Publication Type:Journal Article
- Keywords:
Cardiopulmonary bypass;
Islets of Langerhans;
Insulin;
C-peptide
- From:
Chinese Journal of Anesthesiology
1995;0(12):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To determine the influence of cardiopulmonary bypass(CPB) on human pancreatic bate cell function. Method:Twenty patients were divided into 2 group, groupⅠ(congenital heart disease,n=10). group Ⅱ(valvular heart disease,n=10). Blood samples were obtained from 20 patients at the following intervals:before anesthesia, before CPB, 15 min following CPB, 5 min after relaxing aorta, 20 min after CPB. The plasma insulin and C-peptide levels were measured with radioimmunoassay double-antibody technique,and blood glucose level with GOD-POD method. Result:The significant increases of blood glucose and insulin levels were observed during and after CPB in both groups(P
