The effect of induction with etomidate or midazolam on the hemodynamics and oxygen consumption in patients with coronary heart disease
- VernacularTitle:咪唑安定和依托咪酯静脉诱导对冠脉搭桥病人血流动力学和氧代谢的影响
- Author:
Weiping CHENG
;
Yuhong WANG
;
- Publication Type:Journal Article
- Keywords:
Etomidate;
Midazolam;
Coronary disease;
Hemodynamics;
Oxygen;
Metabolism
- From:
Chinese Journal of Anesthesiology
1997;0(11):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective: To evaluate the hemodynamics and oxygen consumption following induction of anesthesia with etomidate or midazolam in patients with coronary heart disease(CAD). Method: Thirty patients were divided into E (etomidate,n=15)and M(midazolam,n=15)groups,receiving a infusion of etomidate or midazolam until their eyelash reflex was lost. After pipeuronium(0.15mg/kg) and fentanyl were administered according to the mean blood pressure,the intubetion was achieved. Hemodynsmic and oxygen data were measured before induction, during induction and 1 min after intubation. Result: Induction caused a significant fall in HR,MAP,SVRI,PVRI and VO_2I in both groups (P
