Overlooked Management and Risk Factors for Anemia in Patients with Intestinal Behcet's Disease in Actual Clinical Practice.
- Author:
Bun KIM
1
;
Soo Jung PARK
;
Sung Pil HONG
;
Jae Hee CHEON
;
Tae Il KIM
;
Won Ho KIM
Author Information
- Publication Type:Original Article
- Keywords: Intestinal Behcet's disease; Anemia; Frequency; Risk factors
- MeSH: Adult; Anemia/drug therapy/epidemiology/*etiology; Behcet Syndrome/blood/*complications/pathology; Blood Sedimentation; C-Reactive Protein/analysis; Dietary Supplements; Disease Management; Female; Humans; Intestinal Diseases/blood/*complications/pathology; Iron/therapeutic use; Male; Middle Aged; Multivariate Analysis; Odds Ratio; Predictive Value of Tests; Risk Factors; Severity of Illness Index; Trace Elements/therapeutic use
- From:Gut and Liver 2015;9(6):750-755
- CountryRepublic of Korea
- Language:English
- Abstract: BACKGROUND/AIMS: Anemia in patients with inflammatory bowel disease significantly affects the quality of life. The aim of this study was to investigate the frequency of and risk factors for anemia and to describe the management of anemia in patients with intestinal Behcet's disease (BD) in actual clinical practice. METHODS: We included 64 patients with intestinal BD who visited the outpatient clinic of a tertiary referral center in June 2011 and had available laboratory data for the subsequent 6 months. RESULTS: Anemia was detected in 26 patients (40.6%). After 6 months, anemia was still present in 14 of these patients (53.8%). The cause of anemia was investigated in eight patients (30.8%), and oral iron supplementation was prescribed to four patients (15.4%). Of these four patients, two (50%) recovered completely within 6 months. Anemia was associated with a high Disease Activity Index for Intestinal Behcet's Disease (DAIBD, p=0.024), erythrocyte sedimentation rate (p=0.003), and C-reactive protein (p=0.049) in univariate analysis. In multivariate analysis, the factor predictive for anemia in patients with intestinal BD was a higher DAIBD (> or =40; odds ratio, 4.08; 95% confidence interval, 1.21 to 13.71; p=0.023). CONCLUSIONS: Although anemia is common in intestinal BD patients, its clinical importance is overlooked in daily practice. Moderate to severe disease activity is predictive of anemia.
