Study on the Correlation between Anti-Varicella—zoster Virus Antibody Titers and Severity of Pain in Patients with Herpes
- VernacularTitle:水痘-带状疱疹病毒抗体与带状疱疹患者疼痛的关系
- Author:
Jie ZHENG
;
Raoqing CANG
;
Weiping LI
- Publication Type:Journal Article
- Keywords:
Herpes zoster Antibodies, varicella-zoster virus
- From:
Chinese Journal of Dermatology
1995;0(01):-
- CountryChina
- Language:Chinese
-
Abstract:
The anti-varicella-zoster virus (VZV) antibody titers were determined with the method of enzyme linked SPA in sera from 68 patients with herpe, zoster(HZ) and in sera from 35 controls. The results were as follows: In the first week after the onset of HZ, the VZV antibody titers were low in the majority of patients and there was a positive correlation with the severity of patient's pain, but no correlation with patient's age. The titers of VZV antibody were markedly elevated during the 2nd and 3rd week after disease onset, and in this period, there was a positive correlation with patient's age and severity of pain, i. e. higher titers of VZV antibody were usually found in older patients with more severe pain. In patients without postherpetic neuralgia (PHN), the titers of VZV antibody almost returned to normal level in 6 months after HZ episode, but in patients with PHN, the titers of this antibody still remained in high level after 1 to 2 years, which showed that there was a close relation between the PHN and VZV antibody. The VZV antibodies in control group were negative or within normal range.
