Toxicity of Large Dose of Cisplatin on Kidney-Pre-vented by Decoction of Radix Astragali seu Hedysariand Poria
- VernacularTitle:芪苓汤预防高剂量顺铂肾毒性的临床和实验研究
- Author:
Jianhua CHEN
;
Suole ZHANG
;
Zhaoming HUANG
;
Hao LONG
;
Jiali ZHU
;
Dehui ZHAO
;
Xiao WANG
;
Liping ZHU
;
Weixin LIU
;
Zhiping LI
- Publication Type:Journal Article
- Keywords:
Cisplatin/toxicity;
renal disease/chemical induction
- From:
Journal of Traditional Chinese Medicine
1993;0(06):-
- CountryChina
- Language:Chinese
-
Abstract:
Clinical observation revealed that combined use of Decoction of Radix Astragali seu Hedysari and Poria withlarge dose of Cisplatin.none of the cases showed ab-normality in BUN,Cr.with improvement of biochemi-cal indices,there was also diuretic actions observed.Ahgdraton contrel group revealed worse result.The ex-periment proves that the Decoction is capable of pre-venting and ameliorating the harmful effect on kidneyinduced by Cisplatin in rats.