The effects of oxygen free radicals on hyperoxia induced-damages of rabbit aortic endothelial cell
- VernacularTitle:氧自由基在高氧所致离体血管内皮细胞损伤中的作用
- Author:
Hai-Tao YUAN
;
Niu TIAN
;
- Publication Type:Journal Article
- Keywords:
Endothelium;
Free radical
- From:
Chinese Journal of Pathophysiology
1986;0(04):-
- CountryChina
- Language:Chinese
-
Abstract:
The changes of morphology, ATP and malonaldehyde (MDA) contents, xanthine oxidase (XO) activity as well as the glutathione peroxidase (GSH-px) activity of rabbit aortic endothelial cells under hyperoxia (100% O_2) for 0-72 hours were studied. We found that cellular morphological changes including swelling, shape variation after hyperoxia were time-dependent; after a temporarily increasing (24hr)(P