STUDY OF THE ALCOHOL KINETICS IN ANIMALS Of ACUTE ALCOHOL POISONING
- VernacularTitle:急性乙醇中毒者体内乙醇动力学研究
- Author:
Xuemei WANG
;
Bingwei HU
;
- Publication Type:Journal Article
- Keywords:
Acute alcohol poisoning;
Alcohol kinetics;
Mathematical mode
- From:
Chinese Journal of Forensic Medicine
1986;0(01):-
- CountryChina
- Language:Chinese
-
Abstract:
Based on the kinetics of alcohol metabolism in animal models,the mathematicalmode for studing of the alcohol kinetics in person of the acute alcohol poisoningwas established.This mathematical mode can be expressed as x(t)=x_0(1-e~(-kat))-k_bt,which allows calculating the absorpion constant (k_a) arld breakdown rate constant(k_b) for alcohol the curve in dynamic change of the alcohol concentration followingadministration of a large amount of alcohal can be obtained the amount of alcoholin human body [x,(t)] after drinking can be checked out.from the urine Theexperimental study in monkeys showed that the parameters derived from the mathe-matical mode agued witk the results obtained from the experiments
