DETERMINATION OF THE COUMATETRALYL IN BIOLOGICAL MATERIALS BY RPHPLC METHOD USING INTERNAL STANDARD
- VernacularTitle:内标监控反相高效液相色谱法测定生物材料中的立克命
- Author:
Jian YAN
;
Youyi YAN
;
Ping GUO
;
Zhangwan LI
;
Tao JIANG
;
- Publication Type:Journal Article
- Keywords:
Coumatetralyl RP HPLC method
- From:
Chinese Journal of Forensic Medicine
1986;0(01):-
- CountryChina
- Language:Chinese
-
Abstract:
A simple,reliable RPHPLC method on ODS column with UV detector for deter-mination of the anticoagulant rodenticide coumatetralyl in animal tissue was developed.1,1′-Bi-(2-Naphthol)was used as an internal standard to check the process ofexperiments.The mean recoveries from the spiked rabbit liver were around 90% atthe levels of 0.4-16mg/kg.The coeffecint of variation of 5 determination was 3.2%.The results showed that this method has a satisfactory reproducibility.The methodis practical for examining poisons in poisoning cases.
