INVESTIGATION ON THE DISTRIBUTION OF Hp SERUMTYPES AND THEIR INHERITANCE IN CHINESE POPULATION IN SHANGHAI AREA
- VernacularTitle:上海地区中国人Hp血清型的分布和遗传调查
- Author:
Luqing KONG
- Publication Type:Journal Article
- From:
Chinese Journal of Forensic Medicine
1986;0(01):-
- CountryChina
- Language:Chinese
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Abstract:
Using polyacrylamide gel electrophoresis the distribution of Hp serumtypes as well astheir inheritance in a Chinese population in Shanghai area was investigated.Among 1,231 unrelated blood donors from the Shanghai Blood Center,the distribution of Hp phenotypeswere Hpl-1,9.91％,Hp2-1,35.34％,Hp2-2,53.94％ and HpO,0.81％respectively.The gene frequencies of Hp~1,Hp~2,and Hp~0 were 0. 2575,0.6650,and0.0778 respectively.Some variants described by other authors were also determined;amongthose variants a new phenotype K-1 was found,which has never been reportedelsewhere.The inheritance of Hp of 96 family members from twenty Chinese pedigreeswas also adapted to the theory of Smithies and Walker.However,the anomalousinheritance of HpO in four families investigated could only be reasonably interpreted bythe presence of a‘silent’gene Hp~0,because there was no evidence of illegitimacy in thesegregation data of genetic markers in other blood group systems.
