Glucose membrane transport studies of blood cells in type 2 diabetes
10.3969/j.issn.1673-4130.2016.18.006
- VernacularTitle:2型糖尿病患者自体血细胞葡萄糖细胞膜转运研究
- Author:
Zhongwei HUANG
;
Caibao GE
- Publication Type:Journal Article
- Keywords:
type 2 diabetes;
ATP;
membrane transport;
glucose
- From:
International Journal of Laboratory Medicine
2016;37(18):2520-2522
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the transport capacity of glucose membrane with blood cells in type 2 diabetes .Methods The anticoagulated blood of T2DM (40 cases) ,Pre‐diabetes(34 cases) ,control group(40 cases) were added to the same volume of saline and ATP ,37 ℃ 3 h .The changes of glucose was observed ,he level and Rate of glucose decreased were calculated .Results The drop‐out value in the groups of ATP was higher than which of salt water(P<0 .05) .In salt groups ,the drop ratio in the T2DM , Pre‐diabetes ,control groups were increaseed in turn .the value of glucose in T2DM was lower than which in control group and in Pre‐diabetes(P<0 .05) .In the ATP groups ,the drop‐out value in T2DM was lower than which in control group(P< 0 .05) .To T2DM patients ,the drop‐out value was (2 .81 ± 0 .52)mmol/L in salt grops ,which was (4 .73 ± 0 .69)mmol/L ,respectively .Conclu‐sion The glucose membrane transporters for T2DM were obstacles ,the obstacles associated with progression of T2DM ,ATP can improve membrane transporter of glucose .
