Wound healing potential of Althaea ofifcinalis lfower mucilage in rabbit full thickness wounds
- Author:
Valizadeh Robab
;
Hemmati Asghar Ali
;
Houshmand Gholamreza
;
Bayat Sara
;
Bahadoram Mohammad
- Publication Type:Journal Article
- Keywords:
Wound;
Antibacterial;
Skin;
Mucilage;
Althaea flower;
Rabbit
- From:Asian Pacific Journal of Tropical Biomedicine
2015;(11):887-893
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To evaluate and practically demonstrate the influence of Althaea ofifcinalis flower mucilage as a plant known in Iran’s and other Middle Eastern countries’ traditional medicine for its wound healing properties.
Methods:Animals were divided into 6 groups of 5 cases including a non-treated group as the negative control group receiving no treatment, a group treated with eucerin as the positive control group, a phenytoin 1%group as a standard group treated topically with phenytoin 1%hand-made ointment, and treatment groups treated with hand-made Althaea ofifcinalis flower mucilage (AFM) ointment in a eucerin base with different concentrations (5%, 10%, 15%).
Results:Among the treatment groups, the AFM 15%ointment showed the best result. Wound healing duration was reduced by the surface application of these groups. Wound closure was completed on Days 14 and 15 in the AFM 15% ointment and phenytoin 1% groups, respectively. No significant difference was observed in healing period between these groups. Conclusions:In conclusion, AFM 15%ointment was found to reduce wound healing time without any significant difference with the phenytoin 1% ointment. The authors suggest increased AFM effectiveness in when combined with phenytoin or other effectual plants.
