The clinical value of 18 F-FDG PET/CT for the patients with ascites of unknown causes
10.11904/j.issn.1002-3070.2016.02.004
- VernacularTitle:18F-FDGPET/CT对不明原因腹腔积液的临床应用价值
- Author:
Pei′ou LU
;
Wenzhi WANG
;
Yingci LI
;
Rui LIU
;
Yumin HU
;
Lijuan YU
- Publication Type:Journal Article
- Keywords:
Ascites;
Positron emission tomography;
Tomography
- From:
Practical Oncology Journal
2016;30(2):114-117
- CountryChina
- Language:Chinese
-
Abstract:
Objective To assess the clinical value of 18 F-FDG PET/CT for the patients with ascites of unknown causes.Methods A total of 106 patients with ascites undergoing 18 F-FDG PET/CT examination was retrospectively studied and 18F-FDG PET/CT imaging was interpreted by two ways.(1)PET/CT(localization):Diagnostic results of PET/CT depended on the degree of 18 F-FDG uptake in peritoneum with CT was trecoted as anatomical localization,and high 18F-FDG uptake in peritoneum was regarded as malignancy.(2)PET/CT(mor-phology):Morphological changes of peritoneum on CT imaging and the degree of 18 F-FDG uptake on PET ima-ging were simultaneously considered when interpreting the diagnostic results of PET/CT.Results In the differen-tial diagnosis of ascites of unknown cause,the sensitivity,specificity and accuracy of PET/CT( localization) were 90.2%,71.1%and 82.1%,respectively.These values of PET/CT(morphology)were 95.1%,93.3% and 94. 3%,and 85.2%of malignant ascites were found primary lesion.The specificity and accuracy of PET/CT( mor-phology)were higher than those of PET/CT(localization)(P=0.002,P<0.001).Statistical difference was not found in both sensitivities.Conclusion PET/CT( morphology) had higher clinical value than PET/CT( localiza-tion) in the differential diagnosis of ascites with unknown cause,and had important significance in detecting pri-mary cause of malignant ascites.