Application of testing serum RBP,coagulation four indexes and platelet parameters in auxiliary diagnosis of severe liver disease
10.3969/j.issn.1673-4130.2016.17.022
- VernacularTitle:血清RB P、凝血四项和血小板指标检测在重症肝病辅助诊断中的应用
- Author:
Hongsheng ZHANG
;
Min ZHANG
- Publication Type:Journal Article
- Keywords:
severe liver disease;
retinol binding protein;
coagulation four indexes;
platelet count;
mean platelet volume
- From:
International Journal of Laboratory Medicine
2016;37(17):2413-2415
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the application value of serum retinol binding protein(RBP) ,coagulation four indexes and platelet indexes in the auxiliary diagnosis of severe liver disease diagnosis .Methods A total of 110 outpatients and inpatients with severe liver disease in our hospital from January 2014 to December 2015 ,including 43 cases of acute chronic severe hepatitis(group A) ,36 cases of liver cirrhosis(group B) ,and 31 cases of liver cancer patients(group C)] ,38 cases of patients with non severe liver disease and 40 individuals undergoing the healthy physical examination person healthy were selected as the research subjects .RBP , coagulation four indexes[plasma prothrombin time(PT) ,activated partial thromboplastin time(APTT) ,thrombin time(TT) and fi‐brin original quantitative(Fib)] and platelet indexes[platelet count(PLT) ,mean platelet volume(MPV) and platelet distribution width(PDW)] were detected in all the research subjects .Results The levels of RBP ,Fib and PLT in the group A ,B and C of se‐vere liver disease were lower than those in the control group and the non‐severe liver disease ,while the levels of PT ,APTT ,TT , MPV and PDW were significantly higher than those in the control group and the non‐severe liver disease group ,differences were statistically significant(P<0 .05 or P<0 .01) .The levels of RBP ,Fib and PLT in the non‐severe liver disease group were lower than those in the control group ,while the levels of PT ,APTT ,TT ,MPV were higher than those in the control group ,but the differ‐ences were not statistically significant(P>0 .05) .Conclusion RBP ,coagulation four indexes and platelet indexes are the important detection indicators in the auxiliary diagnosis of severe liver disease ,therefore clinic should strengthen the above indexes detections in the patients w ith severe liver disease .
