The neural function analysis based on PET/CT localization of the MRI negative epilepsy The neural function analysis based on PET/CT localization of the MRI negative epilepsy

VernacularTitle:基于PET/CT神经功能分析对MRI阴性癫痫的定位
Author: Yunbo LI ; Youmin GUO ; Xing'an LIU ; Miao WANG
Publication Type:Journal Article
Keywords: drug refractor epilepsy; epileptogenic focus; neural function analysis; preoperative localization
From: Journal of Practical Radiology 2016;32(7):1001-1004
CountryChina
Language:Chinese
Abstract: Objective To explore the neural function analysis based on PET/CT imaging for the MRI negative localization in patients with refractory epilepsy.Methods 85 cases of drug refractory epilepsy patients (male 47,female 38,M/F:1.2 ︰ 1;age range from 6-35 years old),receiving head PET/CT conventional imaging in the interphase,compared to the normal PET cerebral metabolic databases.Surgery was carried out on the patients who with unilateral lobe of the brain,the efficacy was evaluated according to the Eagle standard.Results Epilepsy in unilateral was 63.5%(54/85 ),bilateral was 28.2%(24/85 )and unclear was 8.3%(7/85 ).6 months,12 months,18 months and 24 months later after surgery in patients who with unilateral lobe,the efficacy reaching the Eagle class Ⅰ and class Ⅱ standards was 61.1% (33/54),61.1% (33/54),61.1% (33/54),59.1% (29/49 ),respectively.Conclusion PET/CT neural function analysis could find epileptogenic zone which was negative in MRI imaging in patients with refractory epilepsy, is one of the important methods of preoperative localization.