Analysis of level change on peripheral blood lymphocyte subgroup,erythrocyte Zinc and hs-CRP concentrations in children with hand-foot-mouth disease

VernacularTitle:手足口病患儿淋巴细胞亚群与红细胞锌及超敏C反应蛋白水平分析
Author: Fan KUANG ;
Publication Type:Journal Article
Keywords: hand,foot and mouth disease; lymphocyte; erythrocyte zinc; C-Reactive protein
From: Chongqing Medicine 2016;(1):69-70
CountryChina
Language:Chinese
Abstract: Objective To explore the level change of peripheral blood lymphocyte subgroup ,the erythrocyte zinc and hs-CRP in children with hand-foot-mouth disease (HFMD) .Methods Children with severe HFMD in this hospital were selected as experi-mental group ,and children in health that received physical examination in this hospital were selected as control group .Level of the peripheral blood lymphocyte subsets ,erythrocyte zine and hs-CRP were detected .Results In the HFMD group ,total T cell percent-age(CD3 + ) ,auxiliary/ induced T cells (CD3 + CD4 + ) percentage ,inhibit/cytotoxic T cells(CD3 + CD8 + ) percentage ,and the eryth-rocyte zine levels were all significantly lower than that of the control group(P< 0 .05) ,while the hs-CRP determination level ,B cells (CD19 + ) percentage were significantly higher than those of the control group(P< 0 .05) .Conclusion Children with severe HFMD have cellular immunity and hormone immunity function disorder and are lack of erythrocyte zinc .And their body cannot effectively resist infection virus ,which can lead to secondary bacterial infection .