Progress of diagnosis and treatment of drug induced liver injury in children
10.3760/cma.j.issn.2095-428X.2016.07.020
- VernacularTitle:儿童药物性肝损害的诊治进展
- Author:
Qingming'ai DUAN
;
Zhongyue LI
;
- Publication Type:Journal Article
- Keywords:
Child;
Drug induced liver injury;
Diagnosis;
Treatment
- From:
Chinese Journal of Applied Clinical Pediatrics
2016;31(7):554-556
- CountryChina
- Language:Chinese
-
Abstract:
Drug induced liver injury(DILI) is one of the most common factors causing liver damage and liver failure in children.And in most cases,patients' manifestations lack characteristic features.Thus,patients will develop gastrointestinal symptoms such as jaundice,nausea,vomiting and abdominal abstention until serious hepatic dysfunction.Futhermore,some patients are likely to develop acute liver failure,even death,without drug discontinuation and timely intervening measures.Early diagnosis and effective therapies considerably make sense.This review aims to illustrate the mechanism,manifestations,diagnosis and treatment of DILI in children,in order to promote the early treatment of the disease,reduce the serious complications and improve survival rate in clinical work.
