Research of autophagy marker molecular LC3-Ⅱ in hepatic ischemia-reperfusion injury
10.3760/cma.j.issn.1673-4203.2016.01.017
- VernacularTitle:自噬标记性分子LC3-Ⅱ在肝脏缺血再灌注损伤中的研究
- Author:
Yubin XU
;
Xu'nan MAO
;
Peijian ZHANG
;
Da LI
;
Feng XUE
;
- Publication Type:Journal Article
- Keywords:
Autophagy;
LC3-Ⅱ;
Reperfusion injury;
Liver
- From:
International Journal of Surgery
2016;43(1):54-57
- CountryChina
- Language:Chinese
-
Abstract:
Surgical resection of liver diseases such as liver cancer,traumatic hepatic rupture,it was often faced with ischemia-reperfusion injury of the residual liver,which significantly increased the risk of surgical treatment and impact the postoperative recovery of patients.Autophagy was a way of programmed cell death after hepatic ischemia reperfusion.When researching hepatic ischemia-reperfusion injury simulated by animal experiments,it ofen detected the level change of autophagy marker molecular LC3-Ⅱ representing the activity of cell autophagy.Now the authors write the research progress of LC3-Ⅱ in hepatic ischemia-reperfusion injury.
