Clinical analysis of pulmonary tuberculosis infection in renal transplantation recipients
10.3760/cma.j.issn.0254-1785.2015.11.006
- VernacularTitle:肾移植术后肺结核确诊病例诊断与治疗的临床分析
- Author:
Long ZHENG
;
Ji'na WANG
;
Guisheng QI
;
Long LI
;
Chao ZHANG
;
Ming XU
;
Ruiming RONG
- Publication Type:Journal Article
- Keywords:
Kidney transplantation;
Tuberculosis;
Bronchofibroscope;
Fiberthoracoscope;
Tuberculin test
- From:
Chinese Journal of Organ Transplantation
2015;36(11):666-670
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the diagnosis and treatment of pulmonary tuberculosis in renal transplantation recipients.Method The clinical data of 8 renal transplantation recipients suffering from pulmonary tuberculosis infection were retrospectively analyzed.Result Fever,cough and expectoration were the most common symptoms,however,lacking typicality.Images of chest Xray and CT scan were various and couldn't verify TB infection from pneumonia.Seven of 8 cases were diagnosed through invasive methods,either bronchofibroscope or fiberthoracoscopy.Immunosuppressants were decreased in all cases.Three-drug regimens,including isoniazide,rifampicin and ethambutol or pyrazinarnide,were administrated as anti-tuberculosis chemotherapy.All the cases were cured,without episodes like acute rejection and liver function impairment.Conclusion Routine examinations are not sufficient to diagnose pulmonary tuberculosis in kidney transplantation recipients.While,invasive methods like bronchofibroscope and fiberthoracoscope are helpful.When diagnosed,patients should receive normative anti-tuberculosis treatment and immunosuppressive agents adjustment,which can benefit the prognosis of pulmonary tuberculosis in renal transplantation recipients.