Study on the application value of aspartate aminotransferase mitochondrial isoenzyme in patients with alcoholic liver disease
10.3969/j.issn.1673-4130.2015.23.037
- VernacularTitle:血清天门冬氨酸氨基转移酶线粒体同工酶检测在酒精性肝病中的应用价值
- Author:
Pei LIU
- Publication Type:Journal Article
- Keywords:
alcoholic liver disease;
aspartate aminotransferase mitochondrial isoenzyme;
alanine amino transferase;
aspar-tate amino transferase;
γ-glutamyl transferase
- From:International Journal of Laboratory Medicine
2015;(23):3451-3452
- CountryChina
- Language:Chinese
-
Abstract:
Objective To analyse the clinical value of aspartate aminotransferase mitochondrial isoenzyme (m‐AST ) determina‐tion in patients with alcoholic liver disease .Methods 61 cases of patients with alcoholic liver disease (observe group) receiving treatment in this hospital from March 2013 to March 2015 and 61 cases of healthy individuals(control group) were enrolled in this study ,and serum levels of m‐AST ,alanine amino transferase(ALT) ,aspartate amino transferase(AST) and γ‐glutamyl transferase (GGT) were detected .Results Compared with the control group ,serum levels of of m‐AST ,ALT ,AST and GGT were increased in the observe group ,there were statistically significant differences (P<0 .05) .In patients with alcoholic liver disease ,after treatment , serum levels of m‐AST ,ALT ,AST and GGT were different among patients with hepatic adipose infiltration ,patients with hepatitis and patients with liver cirrhosis ,there were statistically significant differences(P<0 .05) .Conclusion Combined with ALT ,AST and GGT ,m‐AST could be utilized as an indicator for diagnosing alcoholic liver disease ,which has clinical significance .
