The research of the influencing factors on short -term efficacy of intravenous thrombolysis of acute ischemic stroke

VernacularTitle:急性缺血性卒中静脉溶栓近期疗效的影响因素研究
Author: Xiu′e WEI ; Haiyan LIU ; Zhonghai TAO ; Yuting HU ; You LYU ; Cuicui ZHANG ; Jialiang FU ; Liangqun RONG
Publication Type:Journal Article
Keywords: Stroke; Brain ischemia; Thrombolytic therapy; Risk factor
From: Chinese Journal of Primary Medicine and Pharmacy 2016;(1):39-41
CountryChina
Language:Chinese
Abstract: Objective To explore the influencing factors on short -term efficacy of intravenous thrombolysis with rt -PA.Methods The clinical data of the 95 acute ischemic stroke(AIS)patients who received thrombolytic therapy were analyze.Multivariate logistic regression analysis was used to determine the possible influencing factors. Results Fifty -six(58.95%)patients had favourable outcomes after thrombolytic therapy for 24 hours.Multivariate logistic regression analysis indicated that diabetes(OR =3.933,95% CI 1.199 ~12.897)and TOAST classification (OR =1.448,95% CI 1.032 ~2.032 )were the independent predictors of short -term outcome.Conclusion Diabetes and TOAST classification are the major influencing factors of short -term efficacy after intravenous thrombolysis with rt -PA.It should pay attention screening patients for intravenous thrombolysis therapy and predicting the efficacy of thrombolysis.