Role of ultrasonic three -dimensional speckle tracking imaging in assessment left ventricular systolic function in patients with uremia before and after hemodialysis
10.3760/cma.j.issn.1008-6706.2016.01.014
- VernacularTitle:超声三维斑点追踪成像评价尿毒症患者血液透析前后左心室收缩功能的研究
- Author:
Gang WANG
;
Caiyun WANG
;
Xing′an YANG
;
- Publication Type:Journal Article
- Keywords:
Echocardiography;
Three -dimensional;
Uremia;
Ventricular function;
Left;
Hemodia-filtration
- From:
Chinese Journal of Primary Medicine and Pharmacy
2016;(1):47-50
- CountryChina
- Language:Chinese
-
Abstract:
Objective To assess the left ventricular global systolic function changes using ultrasonic three -dimensional speckle tracking imaging (3 D -STI )in patients with uremia undergoing high -flux hemodialysis (HFHD)treatment.Methods 86 patients with uremia and 59 healthy volunteers were selected.Participants of control group underwent plasma brain natrinuretic peptide(BNP)examinations before 3D -STI examinations.All the uremia patients received HFHD therapy,and underwent BNP and 3D -STI examinations before and after 4 weeks HFHD therapy.Parameters of left ventricular three dimensional global area strain(GAS),global circumferential strain (GCS),global longitudinal strain(GLS)and global radial strain(GRS)were measured in each group.The correlation between each 3D -STI parameters and BNP level were analyzed.Results Compared with the control group,GAS, GCS,GLS and GRS of left ventricular were significantly lower(t =7.564,6.866,7.946,5.477,all P <0.05)and BNP level in the control group were significantly higher in the uremia group[(60.75 ±17.22)ng/L vs.(792.68 ± 184.56)ng/L,t =30.876,P <0.05].After HFHD therapy 4 weeks,GAS,GCS,GLS and GRS of left ventricular were significantly higher(t =4.233,5.933,6.546,2.959,all P <0.05)and BNP level were lower(t =27.533,P <0.05) than before treatment in the uremia group.GAS,GCS,GLS and GRS of left ventricular were negatively correlated with BNP level(r =-0.51,0.64,-0.46,-0.43,all P <0.05).Conclusion 3D -STI can accurately evaluate the changes of left ventricular global systolic function in patients with uremia before and after hemodialysis,and provide reliable basis for clinical treatment and efficacy assessment.
