Study on the validation for reference intervals of adult blood cell analysis
10.3969/j.issn.1673-4130.2015.17.020
- VernacularTitle:成人血细胞分析参考区间适用性验证探讨
- Author:
Yinfang YANG
;
Lei ZHANG
;
Chao HE
;
Lin LI
;
Yanping LI
;
- Publication Type:Journal Article
- Keywords:
blood cells;
verification of reference intervals;
reference individuals
- From:
International Journal of Laboratory Medicine
2015;(17):2502-2504
- CountryChina
- Language:Chinese
-
Abstract:
Objective In order to verify the validation of the industry standard WS/T 405‐2012 about adult blood cell analysis reference range ,and ensuring their clinical application .Methods According to Clinical and Laboratory Standards Institute(CLSI) C28‐A3 recommendation method ,40 health reference individuals were enrolled in the study whose blood samples were collected ,de‐tected and analyzed .Results The blood cell analysis indicators involved in the validation included WBC ,RBC ,hemoglobin(HGB) , hematocrit(HCT) ,mean corpuscular volume(MCV) ,mean corpuscular hemoglobin(MCH) ,mean corpuscular hemoglobin concen‐tration(MCHC) ,platelet(PLT ) ,etc .The probability of all results of selected 40 reference individuals beyond the WS/T 405‐2012 blood cell analysis reference interval were no more than 10% (value 90% or higher) .Conclusion The WS/T 405‐2012 blood cell a‐nalysis reference range is suitable for the laboratory .A perfective verification system should be established to ensure its application .
