Voltammetric quantitation of nitazoxanide by glassy carbon electrode
- Author:
Jain Rajeev
;
Yadav Kumar Rajeev
;
Rather Ahmad Jahangir
- Publication Type:Journal Article
- Keywords:
Nitazoxanide;
Squarewave voltammetry;
Glassy carbon electrode;
Pharmaceutical formulation
- From:
Journal of Pharmaceutical Analysis
2013;(6):452-455
- CountryChina
- Language:Chinese
-
Abstract:
The present study reports voltammetric reduction of nitazoxanide in Britton-Robinson (B-R) buffer by cyclic and square-wave voltammetry at glassy carbon electrode. A versatile fully validated voltammetric method for quantitative determination of nitazoxanide in pharmaceutical formulation has been proposed. A squrewave peak current was linear over the nitazoxanide concentration in the range of 20-140 mg/mL. The limit of detection (LOD) and limit of quantification (LOQ) was calculated to be 5.23μg/mL and 17.45μg/mL, respectively.
