A Clinical Study On Liver Abscess For Recent 15 Years In Gwangju-Chonnam Province.
- Author:
Tae Jin SEO
1
;
Chang Hwan PARK
;
Seung Hwan LEE
;
Soo Jung LEE
;
Jae Hong PARK
;
Jeong Ho PARK
;
Wan Sik LEE
;
Young Eun JOO
;
Hyun Su KIM
;
Sung Kyu CHOI
;
Jong Sun REW
;
Sei Jong KIM
Author Information
1. Department of Internal Medicine, Chonnam National University Medical School, Gwangju, Korea. sodium77@naver.com
- Publication Type:Original Article
- Keywords:
Liver abscess;
SIRS;
C-reactive protein
- MeSH:
Biliary Tract;
Bilirubin;
C-Reactive Protein;
Diagnosis;
Female;
Humans;
Incidence;
Jeollanam-do;
Klebsiella pneumoniae;
Liver Abscess*;
Liver Abscess, Amebic;
Liver Abscess, Pyogenic;
Liver*;
Lung Diseases;
Male;
Mortality;
Suppuration;
Systemic Inflammatory Response Syndrome
- From:Korean Journal of Medicine
2005;68(1):26-38
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
BACKGROUND: The mortality of liver abscess markedly decreased because of the improvement of diagnosis and treatment modalities, however, the incidence is still high and various complications have been developed. Our study was to clarify the clinical features, complications, changing patterns of causative organisms and predicting parameters for development of complications in liver abscess. METHODS: We reviewed 197 cases of pyogenic and amebic liver abscesses treated at Chonnam University Hospital from January 1989 to March 2003. These cases were divided into subgroups by time of occurrence, and the data was reviewed comparatively. Predicting parameters for development of complications in recent 5 years were also analyzed. RESULTS: The male to female ratio was 1.59 : 1 and the peak incidence age of liver abscess was in the 7th decade. There were no significant interval changes in incidence of pyogenic liver abscess (96.4%) and amebic liver abscess (3.6%) from January 1989 to March 2003. The most common infection route in pyogenic liver abscess was biliary tract (45.8%), followed by cryptogenic cause (44.2%), pulmonary disease (2.6%), hematogenous (2.1%) and abdominal trauma (1.5%). The pus culture came out positive in 50.4% of pyogenic liver abscess. Klebsiella pneumoniae was the most commonly isolated organism in pyogenic liver abscess (32.9%). The significant predicting parameters for development of complications were age (>or=60), systemic inflammatory response syndrome (SIRS, >or=2 factors), C-reactive protein (CRP, >or=8 mg/dL), bilirubin (>or=2 mg/dL), albumin (<3 g/dL) and AST (>or=200 IU/L, p<0.05). CONCLUSION: There were no significant interval changes in etiologies and predisposing conditions of liver abscess in Gwangju-Chonnam Province from January 1989 to March 2003. Age, SIRS, CRP, bilirubin, albumin and AST were considered as significant predicting parameters for development of complications in liver abscess.
