The follow-up study of mid-term cognitive decline among Chinese TIA/minor stroke cases
10.3936/j.issn.1002-0152.2015.02.007
- VernacularTitle:短暂性脑缺血发作及轻型卒中患者认知功能下降的随访研究
- Author:
Jie YANG
;
Tengfei QU
;
Longchang XIE
;
Jianrui YIN
;
Shuxiang PU
;
Xin'guang YANG
;
Yihua HE
;
Haiyan YAO
;
Cong GAO
- Publication Type:Journal Article
- Keywords:
Transient ischemic attack;
Minor stroke;
Cognitive decline
- From:
Chinese Journal of Nervous and Mental Diseases
2015;45(2):98-101
- CountryChina
- Language:Chinese
-
Abstract:
Objetive The present study was aimed to explore the risk factors of mid-term cognitive decline in pa?tients with indexed TIA/minor stroke (NIHSS≤3) in a Chinese hospital-based cohort. Methods We recruited all consec?utive Chinese TIA/minor stroke patients from July to December in 2012 and followed them up in stroke clinics at 3 and 18 months after indexed TIA/minor stroke. The outcome was defined as significantly cognitive decline at 18 months com?pared with that at 3 months. Results A total of 209 consecutive Chinese TIA/minor stroke cases completed their fol?low-up investigation. Among them, 24 (11.5%) exhibited significantly cognitive decline. The independent risk factors of cognitive decline post TIA/minor stroke were education years (OR=0.869,P=0.021), atrial fibrillation(OR=5.950, P=0.001) and multiple silent lacunar infarcts (OR=5.179,P=0.020). Conclusion It is necessary to evaluate the cognition among TIA/minor stroke cases and a close follow-up is required for patients with atrial fibrillation and multiple silent la?cunar infarcts frequently in order to decrease the risk of cognitive decline post TIA/minor stroke.
