Distribution and antibiotic resistance of pathogens isolated from patients with stroke-associated pneumonia in Department of Respiratory Medicine
- VernacularTitle:呼吸科病房卒中相关性肺炎病原体的分布及耐药性分析
- Author:
Jun WU
;
Ling ZHANG
- Publication Type:Journal Article
- Keywords:
stroke-associated pneumonia;
pathogen;
drug resistance
- From:
Chinese Journal of Infection and Chemotherapy
2015;(3):217-221
- CountryChina
- Language:Chinese
-
Abstract:
Objective To analyze the distribution ,antibiotic resistance of the pathogens isolated from patients with stroke‐associated pneumonia (SAP) in Department of Respiratory Medicine for better clinical medication .Methods The SAP patients who were treated in the hospital from January 2007 to January 2014 were included in this study .The pathogens were cultured and isolated .Antimicrobial susceptibility of these pathogens was analyzed retrospectively .The multidrug resistant bacteria were identified .Pathogen distribution was compared between the pneumonia associated with cerebral hemorrhage and that associated with cerebral infarction .Results A total of 50 strains of bacterial pathogens were isolated from 40 (12 .3% ) of all the 325 SAP patients ,including 46 strains of gram negative bacilli (92 .0% ) (mainly P . aeruginosa ,15 ;E . coli ,11 ;A . baumannii ,5 ;and S .marcescens ,5) and 4 (8 .0% ) strains of S .aureus ,all resistant to methicillin (MRSA) .P .aeruginosa isolates were not resistant to imipenem or aminoglycoside antibiotic ,but highly resistant to the third generation cephalosporins . E .coli strains were not resistant to imipenem or piperacillin‐tazobactam .A .baumannii strains were all multi‐drug resistant . At least 40% of these strains were resistant to imipenem ,aminoglycosides or the fourth generation cephalosporins .All the 4 were gram negative bacilli in Department of Respiratory Medicine ,mainly non‐fermentative bacteria and Enterobacteriaceae , most of which were multi‐drug resistant .MRSA is becoming an important pathogenic bacteria .The prevalence of E .coli is significantly different between the pneumonia associated with cerebral hemorrhage and that associated with cerebral infarction .
