Autophagy and obesity
10.3969/j.issn.1006-6187.2015.04.023
- VernacularTitle:自噬和肥胖
- Author:
Lin ZHANG
;
Mao-qing HU
- Publication Type:Journal Article
- Keywords:
Autophagy;
Obesity;
Hypothalamus;
Adipogenesis
- From:
Chinese Journal of Diabetes
2015;(4):372-374
- CountryChina
- Language:Chinese
-
Abstract:
[Summary] Autophagy is an intracellular degradation process by which the damaged organelles and macromolecules are lysosomal dependently degraded by auto‐phagocyte under the control of autophagy‐related genes. The autophagy level in hypothalamus and adipose tissue changes in obese individuals.Autophagy participates in the regulation of food intake and energy balance ,and associates with adipocyte differentiation and adipogenesis. More and more attention has been paid to the relationship between autophagy and obesity w hich may guide the new research direction of pathogenesis study and therapy of obesity.
