Evaluation of chemopreventive potentials of ethanolic extract of Ruta graveolens against A375 skin melanoma cells in vitro and induced skin cancer in mice in vivo.
- Author:
Ghosh, Samrat
;
Sikdar, Sourav
;
Mukherjee, Avinaba
;
Khuda-Bukhsh, Anisur Rahman
- Publication Type:Journal Article
- From:
Journal of Integrative Medicine
2015;13(1):34-44
- CountryChina
- Language:English
-
Abstract:
Chemopreventive approach with natural products, particularly plants and plant-derived ones, is receiving increasing attention for their effective role against cancer without any palpable side effects. In this study, efficacy of ethanolic extract of Ruta graveolens (RG) on skin melanoma cells (A375) in vitro and on 7,12-dimethylbenz(a)anthracene (DMBA)-induced skin cancer in vivo has been tested in Swiss albino mice.
