The mechanism research of EGFR-TKI resistance
10.3760/cma.j.issn.1673-422X.2014.07.010
- VernacularTitle:表皮生长因子受体-酪氨酸激酶抑制剂的耐药机制
- Author:
Xing′an XIONG
;
Meng WANG
;
Zhiqiang CAI
;
- Publication Type:Journal Article
- Keywords:
Receptor,epidermalgrowthfactor;
Drugresistance,neoplasm;
Tyrosinekinaseinhibitor
- From:
Journal of International Oncology
2014;(7):515-517
- CountryChina
- Language:Chinese
-
Abstract:
Epidermalgrowthfactorreceptor-tyrosinekinaseinhibitor(EGFR-TKI)resistanceinnon-small cell lung cancer(NSCLC)has become more and more common,which includes primary and secondary resistance.The primary resistance is mainly related with EGFR gene mutation,and the secondary resistant is mainly related with T790M,MET and other genes.
