The value of gemstone spectral imaging in assessment pathological features of esophageal carcinoma
10.3760/cma.j.issn.1006-9801.2014.06.004
- VernacularTitle:宝石能谱CT在判断食管癌病理特点中的应用
- Author:
Jianxin ZHANG
;
Mailin CHEN
;
Xiaosong DU
;
Li'na HOU
;
Lei XIN
;
Xiaotang YANG
;
Jun WANG
- Publication Type:Journal Article
- Keywords:
Esophageal neoplasms;
Tomography,X-ray computed;
Gemstone spectral imaging
- From:
Cancer Research and Clinic
2014;26(6):377-380
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate the clinical value of gemstone spectral imaging (GSI) in preliminary assessment of esophageal carcinoma pathology features.Methods 58 patients were analyzed which were diagnosed with histological pathology as esophageal carcinoma underwent GSI enhanced scans before surgery.The iodine concentrations (IC) in the lesions were measured on the iodine-water based material-decomposition images.The results of IC value were evaluated retrospectively with different pathological grading,locations and pathological morphology according to the final pathologic findings.Results 52 cases patients were squamous cell carcinoma and 6 patients were adenocarcinoma.The IC values were (14.75±4.24) mg/ml and (12.86±5.09) mg/ml.The IC value between the two different pathological types had not statistically difference (P =0.35).The IC of different pathological grading:Well differentiation was (20.08± 4.66)mg/ml,n =19.Medium was (14.13±3.39) mg/ml,n =25.Poor was(11.73±3.21) mg/ml,n =14.The IC values between pathological grading had significant difference(P =0.00).There were four different pathological morphology including m edullar (n =16),m ushroom type (n =21),ulcer (n =13) and narrow type (n =8).Their IC values respectively were (16.34±2.56) mg/ml,(18.70±3.03) mg/ml,(14.31±4.60) mg/ml and (11.18±2.09) mg/ml.The IC value between mushroom and narrow type had statistical difference (P =0.04).The Other types had no statistically difference (P =0.19).Conclusions The results of this study demonstrate that GSI has a certain ability of pathologic stage of esophageal cancer.The GSI has a certain clinical value in guiding treatment and judging prognosis of esophageal carcinoma.
