Study on Quality Standard for Compound Jieyu Granules
- VernacularTitle:复方解郁颗粒的质量标准研究
- Author:
Xiangyu LIU
;
Minqiang TIAN
;
Lili FENG
;
Xiang WANG
;
Dongxing ZHANG
;
Wei ZHANG
;
Tiantian LIU
;
Jin'e PENG
;
Yan SUN
;
Yueqi Wang
- Publication Type:Journal Article
- Keywords:
Compound Jieyu granules;
TLC;
HPLC;
Quality standard
- From:
China Pharmacist
2014;(5):763-766
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To establish the quality control method for compound Jieyu granules. Methods:Liquorice was identified by TLC. saikosaponin a, Saikosaponin d and rutin were determined by HPLC. Results:The spots on TLC plates were clear without any in-terference. The linearity was achieved within the range of 0. 508-16. 200 μg (r=0. 999 8) for saikosaponin a, 0. 503-16. 100 μg(r=0.999 7) for saikosaponin d, and 0.130-4.250 μg(r =0.999 9) for rutin. The average recovery was 99.7%(RSD =2.03%), 99. 8%(RSD=1. 44%) and 102. 6%(RSD=1. 40%), respectively. Conclusion:The method is simple, reliable and accurate, and can be applied as the quality control method for compound Jieyu granules.
