S-1 as first-fine treatment for advanced gastric cancer
10.3760/cma.j.issn.1673-422X.2014.03.016
- VernacularTitle:替吉奥一线治疗晚期胃癌的研究进展
- Author:
Feng'e JIANG
;
Ping SUN
- Publication Type:Journal Article
- Keywords:
Stomach neoplasms;
Drug therapy;
S-1
- From:
Journal of International Oncology
2014;41(3):211-213
- CountryChina
- Language:Chinese
-
Abstract:
Patients with advanced gastric cancer lose the surgical indications.Chemotherapy can improve the overall survival and quality of life,which is the main treatment option.But there is no standard chemotherapy regimen for the patients with advanced gastric cancer.Since its initial approval,S-1 is widely used in gastric cancer.Several studies were performed to explore combinations of S-1 with other cytotoxic drugs such as platinum,docetaxel,paclitaxel,and irinotecan.All these combinations were found to be promising,with response rates of around 40％-50％ and relatively favorable safety profiles.
