Analysis of imaging and clinical feature of leukoencephalopathy with hearing loss first complaint
10.3969/j.issn.1001-1781.2009.22.003
- VernacularTitle:首诊为听力下降的脑白质病患者影像学及临床特征分析
- Author:
Lin'e WANG
;
Daoxing ZHANG
;
Qingxue MA
;
Qiming XUE
;
Yanchen XIE
- Publication Type:Journal Article
- Keywords:
leukoencephalopathy;
hearing loss;
imaging;
clinical feature
- From:
Journal of Clinical Otorhinolaryngology Head and Neck Surgery
2009;(22):1014-1017
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To investigate the imaging and clinical feature of leukoencephalopathy with hearing loss first complaint.Method:The head MRI and clinical feature of 7 cases leukoencephalopathy with hearing loss first complaint were retrospectively analysed,including their place,shape,range and blood plasma very-long-chain fatty acid(VLCFA).Result:The head MRI of 2 cases shows symmetry distributed long T_1 and T_2 signal like butterfly aliform in white matter beside both cornu posterious ventriculi lateralis.The head MRI of 5 cases shows abnormal long T_1 and T_2 signal in different part in Alba.The pathological changes often located in white matter of frontal lobe and secondly beside both eornu posterious ventriculi lateralis.The shape shows little patching in 7 cases.The range only shows beside cornu posterious ventriculi lateralis in 2 cases.The range only shows in frontal lobe in 1 cases.Two or more than two parts shows in the rest 5 cases.The result of VLCFA is normal in 3 cases.The rest 4 cases refused to have examination of VLCFA. Conclusion:The patient who firstly complained of hearing loss should be routinely done head MRI.The head MRI imaging could clearly show abnormal white matter in order to avoid omitting existent pathological changes.