The clinical characteristics of histiocytic necrotizing lymphadenitis:analysis of 11 cases
10.3969/j.issn.1001-1781.2009.15.002
- VernacularTitle:组织细胞坏死性淋巴结炎11例临床分析
- Author:
Yulin HUANG
;
Jian'gang LIANG
- Publication Type:Journal Article
- Keywords:
histiocytic necrotizing lymphadenitis;
biopsy;
glucocorticoid
- From:
Journal of Clinical Otorhinolaryngology Head and Neck Surgery
2009;(15):676-677
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To study the clinical features of histiocytic necrotizing lymphadenitis. Method: Eleven pa-tients with histiocytic necrotizing lymphadenitis were collected to analyze the clinical features, pathological features of biopsy lymph nodes,diagnosis and treatment. Result:Lymph node swelling of neck and persistent fever were de-tected in all patients. The leukocyte reduction and swiftness of ESR in serum were detected in most patients. The final diagnosis of histiocytic necrotizing lymphadenitis was confirmed by biopsy investigation of the pathology. The pathological features included distinctive necrosis, loss of lymph node structure, infiltration with histiocytes and lymphocytes, absence of neutrophils. All patients were treated with glucocorticoid for 2 to 4 months. The patients improved significantly and were not recurrence during follow up visit. Conclusion: There was no specific clinical manifestation of histiocytic necrotizing lymphadenitis and which easy to misdiagnose. Diagnosis of histiocytic ne-crotizing lymphadenitis relies on the pathological examination of enlarged lymph nodes.
