Analysis of hypothalamic-pituitary-adrenal axis function in type 2 diabetic patients with different levels of HbA1C
10.3760/cma.j.issn.1000-6699.2011.05.008
- VernacularTitle:不同糖化血红蛋白水平的2型糖尿病患者下丘脑-垂体-肾上腺轴功能分析
- Author:
Jun ZHOU
;
Ru-xue ZHANG
;
Zheng-ping JIA
;
Xiao-hong LUO
;
Yi-zhen JIANG
;
Jing LI
;
Jian-ggo QIU
;
Yun BAO
- Publication Type:Journal Article
- Keywords:
HbA1C;
Hypothalamic-pituitary-adrenal axis;
Diabetes mellitus,type 2
- From:
Chinese Journal of Endocrinology and Metabolism
2011;27(5):392-394
- CountryChina
- Language:Chinese
-
Abstract:
Hypothalamic-pituitary-adrenal(HPA)axis-related factors in patients with type 2 diabetes were studied according to different levels of HbA1C.It showed that HPA axis was normal in HbA1C≤ 7% group[ACTH (18.03±8.39)ng/L,blood cortisol(49.22±8.68)μg/L],hyperactive in 7%11% group with weak feedback regulation[ACTH(26.08±15.41)ng/L,blood cortisol(55.64±24.27)μg/L].These results suggest that HPA axis-related factors in type 2 diabetic patients are different with different grades of glucose metabolic turbulence.