Experimental study of shaped bone substitude made from allogenic in bone defect repairing
- VernacularTitle:复合塑形人工骨修复不规则骨缺损的机制研究
- Author:
Zhiyong FAN
;
Wanchun WANG
;
Caijiang SHUN
;
- Publication Type:Journal Article
- From:
Chinese Journal of Tissue Engineering Research
2001;5(8):53-54
- CountryChina
- Language:Chinese
-
Abstract:
Objective To improve the efficienct of bone defect reparing,we produced a new shaped bone substitude.And we study the result from repairing rabbit radial segmental defect.Method Twenty mature rabbits were made segmental radial defect on both sides.15 received allogenic bone powder/FS/BMP in the left,and allogenic bone powder/FS in the right.5 samples received no implant in the left as control and allogenic bone powder/FS in the right.4,8,12 weeks after operation,result were assessed by gross,radiographic and histologcal examination.Result the study showed that allgonic bone powder/FS/BMP was much faster and better than allogenic bone powder/FS in repairing the defect(P<0.05),Conclusion It is suggest that allogenic bone power/fs/BMP is a kind of high bone induce ability ,shaped,and absorbable bone substitute.