The Effect of "Xingnao Kaiqiao" Acupuncture on the Expression of Peroxiredoxin VI in the Ischemin Cortex of Rats
- VernacularTitle:"醒脑开窍"针刺法对脑缺血大鼠脑皮质Peroxiredoxin Ⅵ表达的影响
- Author:
Huiyan SHI
;
Guangan WANG
;
Jingrong WEN
;
Xiaofeng ZHAO
;
Shu WANG
;
Xuemin SHI
;
- Publication Type:Journal Article
- Keywords:
Peroxiredoxin VI;
XinNnao KaiQiao;
Acupuncture(XNKQ);
Cerebral ischemia
- From:
Journal of Medical Research
2009;38(8):22-24
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate and observe the expression of Peroxiredoxin Ⅵ in iechemia cortex of rats and the intervention effect of Xingnao Kaiqiao Acupuncture(XKA) therapy. Methods Through western blotting,we detected the expression of Peroxiredoxin Ⅵ in xingnao kaiqiao group , comparison group, model group and sham operation group in middle cerebral artery occlusion (MCAO)model of rats. Results At 6h, the expression of Peroxiredoxin Ⅵ in xingnao kaiqiao group , comparison group and sham operation group was increased than that in moddle group,of which Xingnao Kaiqiao group increased obviously(P < 0.05). At 24h, as compared with modlegroup, the expression of Peroxiredoxin Ⅵ in xingnao kaiqiao group and comparison group increased significantly (P < 0.05). Conclusion Xingnao Kaiqiao Acupuncture therapy could raise the expression of Peroxiredoxin Ⅵ in focal cerebral ischemia of rats, and the effect is better that of traditional acupuncture therapy in the earlier period.It is benefit to elevating the ability of antioxygen of focal cerebral ischemia of rats.
