One-year Report on the Fast Elimination of Malaria by Source Eradication (FEMSE) Project in Moheli Island of Comoros
- VernacularTitle:Moheli岛快速灭源灭疟法实施1年报告
- Author:
Guoqiao LI
;
Jianping SONG
;
Changsheng DENG
;
Moussa Mohamed
;
Ahamada MSA Mliva
;
Fatihou Oithik
;
Peiquan CHEN
;
Bo TAN
;
- Publication Type:Journal Article
- Keywords:
ARTEQUICK-PIPERAQUINE-PRIMAQUINE/therapeutic use;
MALARIA/drug therapy;
FAST ELIMINATION OF MALARIA BY SOURCE ERADICATION
- From:
Journal of Guangzhou University of Traditional Chinese Medicine
2010;27(1):90-98
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the therapeutic effect of the method of Fast Elimination of Malaria by Source Eradication (FEMSE) in Moheli island of Comoros. Methods Based on the FEMSE project, parasite positive cases were given a standard treatment course of ARTEQUICK (artemisinin plus piperaquine) plus primaquine: two tablets for adults at 0 hour and two tablets at 24 hours, a total of 4 tablets during one treatment course. One time of Mass Drug Administration (MDA) was for the children with parasite carrier rate less than 10%. Two times of MDA was for the children with parasite carrier rate more than 10%, and the interval between the two MDA was 42 days. Coverage rate for MDA and population carrier rate were observed. Results The number of people taking the first MDA of Artequick-Primaquine was 32,519 (the whole population registered at the same time being 37,243, 367 infants under 6 months old not involved), and the coverage rate for MDA was 88.2%. The population involved in the second MDA was 35,370 (the whole population registered at the same time being 37,112, 335 infants under 6 months old not involved), and the coverage rate for MDA was 96. 2%. Parasite carrier rate was 22.95% (281/ 1,224) before MDA, 1.41% (28/1, 987) two months after MDA and 0. 33% (8/2,458) four months after MDA, with a decrease of 98.56% . Conclusion The decrease of parasite carrier rate from 22. 95% to 0. 33% before and after MDA indicates that MDA of Artequick-Primaquine based on FEMSE can decrease the parasite carrier rate in a short time, without any obvious side effects. Further decrease of parasite carrier rate and incidence will be achieved if the measures for clearing malaria are fully implementated during the consolidation phase.
