The study of intimal-medial thickness （IMT）of carotid, femoral and common iliac arteries in patients with coronary artery atherosclerosis
- VernacularTitle:超声检查冠心病患者颈动脉、股动脉、髂总动脉内-中膜厚度的研究
- Author:
Bin GENG
;
Tiesheng CAO
;
Yunyou DUAN
;
- Publication Type:Journal Article
- From:
Chinese Journal of Ultrasonography
2001;10(5):295-297
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate regularity of intimal-medial thickness（IMT）of extracoronary artery (including carotid, femoral and common iliac arteries ) in patients with coronary artery disease (CAD).Methods Atherosclerosis of carotid, femoral and common iliac arteries was investigated with ultrasound in 115 subjects undergone coronary arteriography (CAG). Stepwise multiple regression analysis and Logistic regression were carried out between the results of extracoronary artery ultrasound examination and CAG.Results The IMT and incidence of carotid, common iliac and femoral atherosclerostic plaques in patients with positive CAG were significantly higher than the subjects with negative CAG (P<0.01); Logistic regression indicated that the presence or absence of carotid, common iliac, femoral atherosclerosis was closely correlated with CAD (β were 2.147, 2.813 and 3.204 respectively,P<0.05,<0.01,<0.005 respectively. Odds ratio were 8.797,16.666 and 24.642 respectively,P<0.001). Stepwise multiple regression analysis showed that common iliac and femoral IMT were closely associated with LOG (1+Gensini′s score) (P<0.0001). For each increased 1 mm of common iliac and femoral IMT, the LOG (1+Gensini′s score) increased 0.20 and 0.19 respectively. Furthermore, the carotid artery IMT was also partly associated with LOG (1+Gensini′s score) (P<0.05). Common iliac atherosclerosis was closely correlated with occurrence of acute myocardial infarction,the positive predictive value of carotid, common iliac, femoral atherosclerosis was 75%, 87%, 88% respectively, the positive predictive values for 2 sites and 3 sites were 92%～98% and 100% respectively.Conclusions The presence or absence and the extent and severity of coronary artery atherosclerosis can be predicted through investigating extracoronary artery atherosclerosis.Common iliac and femoral arteries can be asurrogate and window for studying the occurrence, progression of coronary artery atherosclerosis.
