The role of HIRA gene in the pathogenesis of congenital heart disease
10.3760/cma.j.issn.1673-4408.2010.01.021
- VernacularTitle:HIRA基因在先天性心脏病发病机制中的作用
- Author:
Jing ZHANG
;
Cuo-ying HUANG
;
- Publication Type:Journal Article
- Keywords:
HIRA;
Conotruncal defect;
22q11 microdeletion
- From:
International Journal of Pediatrics
2010;37(1):65-68
- CountryChina
- Language:Chinese
-
Abstract:
Conotruncal defects(CTD) is a kind of severe cardiovascular abnormality, which is the major cause of death in rinatal pelriod. Some researches suggest that CTD and 22q11 microdeletion had close relationship. In addition, HIRA gene is located in 22q11, which was speculated as a candidate gene in CTD.
