The cost-effectiveness analysis in patients with primary hypertension by different drug treatment WANG
10.3760/cma.j.issn.1008-6706.2010.12.020
- VernacularTitle:不同药物治疗原发性高血压的成本-效果分析
- Author:
Zhou-yan WANG
- Publication Type:Journal Article
- Keywords:
Hypertension;
Benazepril;
Perindopril;
Amlodipine;
Nitrendipine;
Economics,pharmaceutical
- From:
Chinese Journal of Primary Medicine and Pharmacy
2010;17(12):1625-1626
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the economic effects in patients with primary hypertension by four kinds of treatment.Methods 160 cases with primary hypertension were randomly divided into Benazepril group(n=40)、Perindopril group(n=40)、Amlodipine group(n=40) and Nitrendipine group(n=40),and data was evaluated with the pharmacoeconomic cost-effective analysis method.Results Hypertensive efficacy in 4 groups were not sig-nificantly different(x2=3.26,P>0.05);The symptom total score before treatment and after treatment was sisnifi-canfly different(a11 P<0.05);The SF-36 Scale after treatment in 4 groups were higher than before treatment(all P<0.05);The costs of pefindopril was lower than the benazepril.Conclusion Pharmacoeconomies played an important role in optimizing therapeutic scheme,guiding rational drug use and increasing economic effectiveness.