Maternal caffeine consumption during pregnancy and the risk of low birth weight
10.3760/cma.j.issn.1671-7368.2017.08.018
- VernacularTitle:孕期摄入咖啡因与低出生体质量新生儿风险的研究进展
- Author:
Hongli QIN
;
Weigang FANG
- Keywords:
Infant,low birth weight;
Caffeine;
Pregnancy
- From:
Chinese Journal of General Practitioners
2017;16(8):633-636
- CountryChina
- Language:Chinese
-
Abstract:
Low birth weight is associated with newborn mortality and adult chronic diseases.Some studies found that naternal caffeine consunption during pregnancy was closely related with low birth weight.Resent research evidence indicates that caffeine may induce low birth weight by blocking adenosine receptors,inhibiting phosphodiesterase(PDE) and enhancing angiotensin Ⅱ (AT2) receptor gene expression to lower the placenta blood flow.We recommend that women should reduce caffeine intake during pregnancy.