Clinical Research on Simvastatin Combined with Tanshinone in the Treatment of Acute Cerebral Infarction
- VernacularTitle:辛伐他汀联合丹参酮治疗急性脑梗死的临床观察
- Author:
Yang LI
;
Tianqi WANG
;
Guobing SUN
- Publication Type:Journal Article
- Keywords:
Cerebral infarction;
Simvastatin;
Tanshinone
- From:
China Pharmacist
2015;18(10):1777-1778,1787
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To analyze the effect of simvastatin combined with tanshinone in the treatment of patients with acute cere-bral infarction. Methods:The patients with acute cerebral infarction were randomly divided into the treatment group (n=50) and the control group (n=50). The control group was given tanshinone treatment, the treatment group was given simvastatin treatment addi-tionally, and the treatment course was 14 d. The NIHSS ( nerve function defect degree) , ADL ( daily life activity) and the treatment effect before and after the treatment were comprehensively evaluated and compared between the two groups. Results: Compared with those before the treatment, the NIHSS and ADL scores were significantly improved in the two groups after the treatment, and the differ-ences were statistically significant (P<0. 05), and the improvement in the treatment group was significantly better than that in the control group with statistical significance (P<0. 05). The total effective rate of the observation group was 98%, which was higher than that (70%) in the control group (P<0. 05). Conclusion: Simvastatin combined with tanshinone in the treatment of acute cerebral infarction shows obvious therapeutic effect, which can obviously improve neurologic deficits and daily life activity, and is worthy of fur-ther clinical application.
