Study on Preparation Process of Huangmai Granules
- VernacularTitle:黄麦颗粒制备工艺研究
- Author:
Linghong XIA
;
Guanqin JIN
;
Li SUN
- Publication Type:Journal Article
- Keywords:
Huangmai granules;
Preparation process;
Icariin;
Stilbene glucoside
- From:
China Pharmacist
2015;(6):901-903,904
- CountryChina
- Language:Chinese
-
Abstract:
Objective: To determine the optimal preparation conditions for Huangmai granules. Methods: Using single factor screening method and orthogonal design method, the extraction process and granulation process were optimized. Results:The optimal preparation process was as follows:the medicinal materials in the prescription were extracted 3 times with 8-fold amount of water with 2h for each time. The water extract was combined followed by vacuum concentration, and then dried to obtain dry extract. The powder of dry extract was evenly mixed with dextrin at appropriate amount, and the wet granules were prepared with the 40% ethanol followed by drying and size stabilization to obtain the products. Conclusion:The selected preparation process is scientific, reasonable and sta-ble, and suitable for the industrial production.