Comparison of the effect of different concentrations of dezocine for postoperative epidural analgesia after cesarean section
10.3760/cma.j.issn.1008-6706.2015.s1.001
- VernacularTitle:不同剂量地佐辛单独应用于剖宫产术后硬膜外镇痛的效果比较
- Author:
Liu XINGUO
;
Su SHIYU
;
Li JIAHUI
- Publication Type:Journal Article
- Keywords:
Anesthesia,Epidural anesthesia;
Analgesia,obstetrical;
Dezocine;
Morphine morphine;
Cesarean section
- From:
Chinese Journal of Primary Medicine and Pharmacy
2015;(z1):1-2,3
- CountryChina
- Language:Chinese
-
Abstract:
Objective To compare the clinical effect and adverse reactions of different concentrations of dezocine epidural anesthesia for cesarean section.Methods According to digital table,120 cases of elective cesarean section were randomly divided into 4 groups with 30 cases in each group, the group D1 was given with dezocine 2.5mg,the group D2 with dezocine 5mg,the group D3 with dezocine 10mg,the group M with morphine 2mg.All the drugs used in postoperative epidural analgesia after cesarean section.To observe resting pain and conduct the VAS scoring at postoperative 4,8,12,24h and record various adveme reactions.Results The VAS scores at postoperative 4,8,12h in the group D1 were lower than those in the D2,D3,M with statistical difference(all P<0.05).The VAS scores at postoperative 4,24h had no statistical difference among D2,D3,M groups(all P>0.05).The VAS scores at postoperative 8h in the group D3 were lower than those in the D2,D3,M with statistical difference(all P<0.05). There were no statistical differences among 4 groups at postoperative 24h(all P>0.05).The incidence rates of nause-a and vomiting the group M were higher than that in the group D1,D2 and D3,showing statistical difference among them(P<0.05).Conclusion Appropriate concentrations of dezocine used in postoperative epidural analgesia after cesarean section has definite effect and less adverse reactions.