Pharmacist-physician Collaboration Based on Toxicological Analysis in the Treatment of One Case of Ro-denticide Poisoning
- VernacularTitle:基于毒物分析医药协作救治鼠药中毒1例
- Author:
Guirong XIAO
;
Jing LIU
;
Ting XU
- Publication Type:Journal Article
- Keywords:
Toxicological analysis;
Pharmacist-physician collaboration;
Bromadiolone;
Rodenticide poisoning
- From:
China Pharmacist
2015;(5):814-815,816
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To share the experience of clinical cooperation of physicians and clinical pharmacists in the treatment of one case of rodenticide poisoning. Methods: One case of rodenticide poisoning was early diagnosed by physicians according to the con-sciousness disorder and coagulation dysfunction. Clinical pharmacists participated in the drug treatment actively through providing vita-min K1 at the dose of 30 mg·d-1 as the treatment dose and monitoring the effectiveness. Toxicology analysis was recommended, and 718 ng·ml-1 bromadiolone was found out in the blood samples. According to the long half-life of bromadiolone, the initial duration of treatment was set at 2-3 months, while follow-up plan and final duration of treatment were defined based on coagulation parameters and poison concentration monitoring results. Results:The patient recovered rapidly after hospitalization due to the cooperation of physicians and clinical pharmacists through quickly correcting diagnosis of physicians and actively participating in medication of clinical pharma-cists. After the 3-month treatment, the coagulation parameters of the patient were normal and the patient was discharged with follow-up. Conclusion:The collaboration of physicians and clinical pharmacists leads to the optimal regimen with early, full dose and long course of vitamin K1 therapy.
