Clinical Efficacy of BCG-polysaccharide Nucleic Acid Cominbed with Isotretinoin in the Treatment of Pa-tients with Plane Warts
- VernacularTitle:卡介苗多糖核酸联合异维A酸治疗扁平疣疗效观察
- Author:
Xing SHAO
;
Xiaoyang ZHANG
- Publication Type:Journal Article
- Keywords:
Plane warts;
BCG-polysaccharide nucleic acid;
Isotretinoin soft capsules;
Efficacy;
Safety
- From:
China Pharmacist
2015;(1):103-104,105
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To study the clinical efficacy and safety of BCG-polysaccharide nucleic acid combined with isotretinoin soft capsules in the treatment of plane warts. Methods:Seventy patients with plane warts were randomly divided into the observation group and the control group(n=35). The control group were treated with isotretinoin soft capsules, limp 10mg, bid, 4 weeks to 10mg, qd. The observation group were given BCG-polysaccharide nucleic acid 1ml, im, every otherday, on the basis of the contrl group. After 8 weeks of treatment, T cell populations and immunoglobulin levels were detected, and the efficacy and adverse reactions were recorded. Results:After the treatment, T cell population level, IgG and IgA of the two groups were significantly improved(P<0. 01), and the improvement in the observation group was significantly better than that in the control group (P<0. 05). The onset time of the observa-tion group was shorter than that of the control group ( P<0. 01). The total effective rate of the observation group was higher than, that of the control group(P<0. 05). The occurrence of adverse reactions in the two groups were no significant(P>0. 05). Conclusion:The clinical efficacy of BCG-polysaccharide nucleic acid combined with isotretinoin soft capsules in the treatment of plane warts is sig-nificant with promising security.
