Study on Anti-RSV Activity of Natural Curcuminoids
- VernacularTitle:天然姜黄素类化合物抗人类呼吸道合胞病毒研究
- Author:
Jie WU
;
Jiaojiao XU
;
Juan YE
;
Dan LI
;
Gang LIU
;
Jinchun SONG
- Publication Type:Journal Article
- Keywords:
Natural curcuminoids;
Curcuma longa;
RSV;
Cytopathic inhibition method
- From:
China Pharmacist
2015;(1):34-37,38
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To study the anti-human respiratory syncytial virus ( RSV) activity of natural curcuminoids in Curcuma lon-ga in vitro. Methods:The anti-RSV activity of ethyl acetate part of 95% ethanol extracts of Curcuma longa and natural curcuminoids in Curcuma longa in vitro were detected by cytopathic inhibition method. Results:Bisdemethoxycurcumin exhibited anti-RSV activity with IC50 of 12. 5 μg·ml-1 and SI of 1. Conclusion:Natural curcuminoids in Curcuma longa exhibit anti-RSV activity.
